There is no perfect measure. Really generalized statement, I realize.
My goto measure is an RCBS Uniflow with a small drum mounted to the right of my RC2. How a measure is mounted makes a difference. I have this one mounted in the older RCBS stand with the steel arm extended out from the bench. The stand is about 4 inches past the edge of the bench with a 1x4 oak mounting board. I can sit in my chair and fill bench blocks, rotate just a little and charge a complete block and repeat. For me, this measure is a good universal measure, but I do not like it for very small cases and a couple of different powders. It handles the basics, W231, Unique, bullseye, all the Dots, 2400, H110, 4227, 4895 really well and does so with good accuracy. I do not like it with very long stick powders, feels very crunchy and starts to vary some, so I then get close and trickle up to what I need. Also some of the fine powders feel bad, but measure well. This measure gets no love when dropping into the 2.2 grain and lower charges, it is not consistent for me.
I do have an old Lyman 55, very good for tiny charges and somewhat a pain to set up. The 3 adjustment cavity seems to work the best if the cavity is deep with the adjusters set to form a straight side wall. This will throw down to the 1.7 and 1.8 grains for my light 32ACP loads and is consistent. I have never used one with any of the third party chamber mods and would love to but can't afford them when they come up. I would kill to have a drop tube for it that was longer and threaded on the outside for a standard die nut and RCBS threaded drop tubes, then I could mount it properly in the RCBS stand and I think it would work better yet. The knocker is key with this measure, does slow the workflow down just a little. Accuracy increased after I made a baffle for it.
I also use a Lee PPM. What a piece of crap! I did lap in the drum to help with the powder dust fallout, it did help but did not fix it. The lever is way to short for general use, the drop tube stinks and no chance of mounting it in a decent stand. I love the idea of the removable hopper, they got that one right. Again, it gains ground with a baffle installed. This is the best adjustable measure I have found for the 1.7-1.9 grain loads for 32ACP! In fact up to my 2.2 - 2.3 grain loads it is the most consistent. I have also loaded 25ACP with this measure and it was good down to about 1.4 grains.
My last measure is the RCBS Little Dandy. This is a different concept in a measure, almost like the Lee dippers with a hopper and no guess work. This measure will mount in steel bar on the RCBS stand, just like the Uniflow with a die nut top and bottom. Not how I use it... I load my loading blocks and hold the measure on each case mouth and rotate the rotor to drop the charge. Does not sound like a big deal, but this really does save time! The only gotcha is that you have to have a rotor that drops the charge you want. You can fudge them smaller with a drop of wax, but they can fall out and must be monitored. You could do it with epoxy or JB Weld, but that becomes a permanent mod and you no longer have a listed rotor. You can also go larger by drilling a small indent in the bottom of the rotor chamber, but again now not a stock rotor. There is an adjustable rotor for the unit made by a third party. This defeats the idea of the known volumetric chamber and requires a scale to set up for each use. The stock rotors are very consistent. There are 28 stock rotors 00, 0 - 26. This is primarily a pistol measure due to the size of the rotors. I love this measure for my cast 380 loads and 22 TCM cast loads.
As you can see, I do not have any of the high end measures and I do not run a progressive press. I spent a lot of time around Dillon 1050's loading commercial ammo with a good buddy. Progressives are perfect in that environment, but I have always been uneasy with the concept and the lack of supervision at each stage. I surely would not load any tiny cases on one, the risk is just to high. It would be nice to make 223, 9mm and maybe 45's on one, but I am just not willing to give up the single stage control. So, I load and cast all winter and shoot all summer.
What measures would I like to try?
I would like to try one of the Lyman 55's with the third party adjustment setups. It would be interesting to have a possibly consistent way to set and preset the measure.
I would also like a Lee Deluxe PPM, not sure that it fixes any of the weaknesses of the PPM but it is a better built measure. I have not found the overwhelming urge to spend 65+ bux on a Lee product and have not found one on the used market yet. I would also like to give the Hornady and Redding a run for their money, but again... more than I want to drop on a measure for my hobby.