I've been using Lyman's 358627 mould - intended for the 357 Max, 215 grains, GC, SWC. In in my alloy it weighs 220 grains. The flat nose put a 2" hole clear through resulting in immediate bleed out. Never had a deer go more than 50 yards with a lung hit, typically drop right there. Use all the IMR 5010 (surplus powder intended for machine gun) I can stuff in the case with a magnum primer (compressed as much as I can). Hunted with that in 30 below and it worked as well as 60 above. Use my own homemade lube 'Glenhills Green' left over my commercial casting days. Used that in the northwoods of WI for over 25 years and never felt undergunned. Accurate enough out to 150 yards to take deer. Cases are necked up WW's - still using cases I stashed in the 80's and 90's. Feeds great in my Remington 700.
Also have a 9.3x57 that I use a Mountain Molds custom 270 & 300 grain in. This I use IMR 3031 and load like a jacketed bullet. Same performance as the 35 Whelen, but in a classier rifle (in my opinion). This one has a too flat of meplat and the nose gets hung up on the ramp. For now I use it single shot, but in the future will either order another mold with less of a nose or have the feed rails modified - havn't made up my mind either way yet.
Started hunting cast with a 35 Remington using Lyman's 358315 in my ignorance. In my defense, no internet and that's what Lyman recommened. That round nose performed so poorly I swore off cast bullets. Put a small hole clean through the deer, but wasn't effective. About 5 years later tried cast again with the Whelen and the SWC and very happy. I'm sure if I used RCBS's flat nose bullet the results would be different.