I have an 80's vintage 45 Colt BH............no need for a 45 ACP cylinder. Nary a piece of ACP brass. Not a SA revolver fan, either. Besides the ROA, that's enough SA revolvers for me.
The 45 BH, found it's home by default. We hunted in the shotgun only zone in lower Michigan. Cindy didn't care for the recoil of 12 gauge slugs. Michigan, just began allowing straight walled pistol cartridges, in handguns for deer. Cindy planned on using my 6" Python. Well Michigan said the firearm has to be registered to the hunter. Prior to that, a friend of mine had a FFl license and just got a deal on three 7 1/2" 45 LC BH's. @ $160 a piece. Asked me if I wanted one. Told him I take one but to hold it till I pulled a purchase permit. PITA, in Wayne county, unless your a woman. So, I had Cindy pull the permit........ Police gave her the royal treatment and she now had a handgun capable of taking deer sized game, registered in her name.
The first season, she use it, she took a spike buck at @ 20 yards. Shot though the heart with RCBS 250 SWC PB. Load was 19 grains of Hercules 2400 (Ruger only) lit with a CCI magnum primer. Couple years later she took a doe, late in the firearms season.
Never had to do any work on the BH. Throats were uniform @ .454 diameter............ loose slip fit with a .454 sized bullet. Besides the 250 RCBS moud, the only other one I use is MP's clone of the 270 SSA, with the HP options. Penta and conic.